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Article
March 1949

VIRUS AS POSSIBLE ETIOLOGIC AGENT OF ERYTHEMA MULTIFORME EXUDATIVUM, BULLOUS TYPE: Report of a Case

Author Affiliations

SALT LAKE CITY

From the George B. Lockhart Memorial Pediatrics Research Laboratory, Department of Pediatrics, University of Utah School of Medicine.

Arch Derm Syphilol. 1949;59(3):251-262. doi:10.1001/archderm.1949.01520280003001
Abstract

CONSIDERABLE confusion exists in regard to the etiology and the interrelationship of a variety of clinical entities involving epithelial structures of the body, the lesion common to all of which is thought to be initially of a herpetic nature.

The entities which form this group involve the palpebral conjunctiva of the eyes, the mucous membranes of and the skin about the mouth, anus and genitalia, the mucous membranes of the oropharynx and bowel and occasionally the skin of the entire body. The disease of this general nature which affects the palpebral conjunctiva has been referred to as the Stevens-Johnson syndrome. This condition, described in 1922 by the men whose name it bears,1 is a severe form of membranous conjunctivitis, associated with gingivostomatitis and generalized eruption of the skin. The presence of fever in cases of this disease led them to suggest the descriptive term "eruptive fever with stomatitis and

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