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March 1949

KERATOSIS BLENNORRHAGICA: Response to Streptomycin; Report of a Case

Author Affiliations

CINCINNATI; Medical Corps, Army of the United States; Consultant in Dermatology and Syphilology, Oliver General Hospital ATLANTA, GA.

From the Department of Dermatology, College of Medicine, University of Cincinnati.

Arch Derm Syphilol. 1949;59(3):284-292. doi:10.1001/archderm.1949.01520280036004

IN THE half-century which has elapsed since the original description of keratosis blennorrhagica by Vidal1 in 1893, it has become generally agreed that this disease represents a distinct clinical entity. In 1942 Keim2 analyzed the disease from an etiologic standpoint and described the fundamental histologic changes. Since that time numerous investigators have anvanced methods of treatment; these have in the main been directed against the general infection, local treatment proving to be of little value.

Among the therapeutic measures reported favorably are intravenous injections of 1 per cent solution of merbromin N. F., (mercurochromeR), by Willmott3 in 1926, and the use of autogenous vaccines, by Scholtz,4 about one year later. Downing5 reported rapid recovery in a patient following double vesiculectomy and prostatotomy. Sherman, Blumenthal and Heidenreich6 stressed the importance of treating the primary focus and stated the opinion that local treatment of the

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