IN THE past few years the Russian literature has included numerous papers dealing with the antireticular cytotoxic serum of Bogomelets. The American Review of Soviet Medicine introduced this subject to the American medical profession with translations of papers by Bogomelets, Marchuk, Linberg and Strazhesko.1 Since then many investigators have instituted research and study of clinical problems to corroborate and check the results reported by the Russian investigators.
At a conference held in July 1942 at Ufa, Soviet Union, the action of antireticular cytotoxic serum was summarized as follows:
Anti-Reticular Cytotoxic Serum, proposed by A. A. Bogomelets, is a powerful specific factor influencing the physiologic system of the connective tissue, exerting a strong stimulative action upon the cellular elements of the system if used in small doses, this having been established both by experimental investigations and clinical observations. Taking into account the fact that the physiologic system of the connective