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Article
May 1949

VOGT-KOYANAGI SYNDROME: Report of a Case

Author Affiliations

NEW YORK

From the Department of Medicine (Dermatology), New York Hospital and Cornell University Medical College.

Arch Derm Syphilol. 1949;59(5):526-530. doi:10.1001/archderm.1949.01520300036006
Abstract

THE SYNDROME of uveitis with poliosis, vitiligo, alopecia and dysacousia, to which the name Vogt-Koyanagi syndrome has been given, has been recognized as a definite clinical entity for four decades. However, reference to it in dermatologic literature is sparse. It has been discussed mainly in ophthalmologic literature, probably because uveitis is the presenting and most disabling manifestation of the syndrome. But its dermatologic features are often striking enough, and of sufficient importance to warrant the attention and interest of dermatologists and the enlistment of their assistance in the investigation of the many mysteries attending this fascinating syndrome.

REVIEW OF THE LITERATURE  Although Schenkl (1873) and Jacobi (1874) had called attention to depigmentation of lashes in association with chronic uveitis1 and although isolated associations of other features, such as Gilbert's (1910) of vitiligo and iridocyclitis, had occurred, it was Vogt2 who, in 1906, first described the syndrome. Koyanagi3

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