The PAUCITY of the literature on the Ehlers-Danlos syndrome in all fields except pediatrics and dermatology would make one believe that the condition has been arrogated by members of these two groups. It seems, however, that the syndrome should have been recognized and emphasized by others. For instance, the orthopedist should have been recording the joint symptoms; the surgeon, the friability of the skin; the roentgenologist, the roentgenologic findings; the pathologist, the tissue changes; the internist, the ecchymoses and hemorrhages, and the geneticist, the familial characteristics. The syndrome, according to Ronchese1 is characterized by (1) hyperlaxity and hyperextensibility of the joints, (2) hyperelasticity and hyperlaxity of the skin and (3) friability and fragility of the skin and blood vessels, with breaking, splitting and formation of hematomas and pseudotumors subsequent to the slightest trauma. The severity of these characteristics may vary among different persons and
JOHNSON SAM, FALLS HF. EHLERS-DANLOS SYNDROME: A Clinical and Genetic Study. Arch Derm Syphilol. 1949;60(1):82–105. doi:10.1001/archderm.1949.01530010085006
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