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Article
October 1949

LIPOMELANOTIC RETICULOSIS OF LYMPH NODES IN A CASE OF LICHEN PLANUS

Author Affiliations

LOS ANGELES

From the Department of Dermatology and Syphilology, University of Southern California School of Medicine.

Arch Derm Syphilol. 1949;60(4):609-613. doi:10.1001/archderm.1949.01530040137010
Abstract

IN 1891 Jadassohn1 described some peculiar histopathologic changes in the lymph nodes observed in a case of pityriasis rubra (Hebra). Subsequently, Pautrier and Woringer2 made a preliminary report on this condition, which they termed "lipomelanotic reticulosis"; and in 1937 they published a detailed study3 of this disorder, which has been observed in conjunction with a variety of dermatoses. This entity can best be described as lymphadenopathy characterized by proliferation of reticular cells, phagocytosis of fat and melanin and pleomorphic cellular infiltrations.

In 1941 Soloff4 reported the occurrence of this specific alteration of lymph nodes in a case of acute miliary tuberculosis. However, in this case it was clearly established that the lipomelanotic changes were not associated with the tuberculosis but had arisen consequent to an intensely pruritic, chronic-recurrent, occupational dermatosis of the groins. Subsequent reports have emphasized the association of lipomelanotic reticulosis with some types

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