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Article
December 1949

LICHEN-SCROFULOSORUM-LIKE LESIONS ASSOCIATED WITH SARCOIDOSIS: Report of a Case

Author Affiliations

CHICAGO

From the Department of Dermatology, University of Illinois College of Medicine, Dr. F. E. Senear, Director.

Arch Derm Syphilol. 1949;60(6):1212-1214. doi:10.1001/archderm.1949.01530070152019
Abstract

Lichen scrofulosorum is characteristically associated with a high degree of sensitivity to tuberculin, patients in up to 67 per cent of cases showing positive reactions to old tuberculin in a dilution of 1: 1,000,000.1 The finding of apparently typical lesions of lichen scrofulosorum in a patient exhibiting negative reactions to intracutaneous injections of old tuberculin in dilutions as low as 1:10 is therefore unusual. Microscopic examination of cutaneous biopsy specimens in this case revealed a histologic structure characteristic of sarcoid, and on further study laboratory and clinical observations of sarcoidosis involving the eye, salivary glands and lungs were made. The association of lichen scrofulosorum with sarcoidosis has been noted on several occasions in cases cited in the transactions of dermatologic society meetings, but the observation of a sarcoidal histologic pattern in lesions of lichen scrofulosorum is apparently unique. Mitchell and Nomlund,2 Cannan,3 Cornbleet,4 Michelson5

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