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Article
January 1950

LYMPHOSARCOMA TREATED WITH NITROGEN MUSTARDReport of a Case

Author Affiliations

MINNEAPOLIS; CINCINNATI

From the Department of Dermatology and Syphilology, University of Minnesota, Dr. H. E. Michelson, director, and the Department of Dermatology and Syphilology, Minneapolis General Hospital, Dr. S. E. Sweitzer, chief.

Arch Derm Syphilol. 1950;61(1):12-19. doi:10.1001/archderm.1950.01530080018002
Abstract

THE USE of the nitrogen mustards in treatment of the lymphoblastoma group of diseases has recently aroused much interest among both clinicians and pathologists, but there are very few reports on the use of this drug in cases of lymphosarcoma cutis.

We had the opportunity to study, from the onset of the initial lesion until death twelve months later, a patient with lymphosarcoma cutis on whom nitrogen mustard therapy was used.

REPORT OF A CASE

A. R., a 75 year old white man, was first seen in the outpatient dermatology service at the Minneapolis General Hospital on Feb. 27, 1947. At that time his sole complaint was a dark red to purple plaque, located in the right preauricular region, which had been present for four weeks. A biopsy of this lesion showed microscopic changes consistent with a diagnosis of lymphorsarcoma. The patient was then admitted to the hospital for

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