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Article
February 1950

PROTEIN DEFICIENCY IN CUTANEOUS DISEASE

Author Affiliations

PITTSBURGH

From the Department of Dermatology and Syphilology, University of Pittsburgh School of Medicine.

Arch Derm Syphilol. 1950;61(2):261-270. doi:10.1001/archderm.1950.01530090091008
Abstract

IN A PREVIOUS presentation,1 the subject of nutritional eczema in the aged was discussed. In it my associates and I presented for consideration observations on patients past middle life who presented varying degrees of edema of the legs below the knees, associated with a chronic, erythematous, papular, vesicular, pustular, exudative or squamous inflammation of the skin involving the same areas. In these patients cardiac decompensation and renal disease were not found and varicose veins of sufficient degree of severity to cause the edma were not present. We suspected deficiency in serum proteins and found in many instances a decreased total serum protein with a reversal of the albumin-globulin ratio. This deficiency in aged persons was due to several factors: poor dentition with attendant low intake of meat, sketchy dietary habits of many elderly people, anorexia and impaired assimilation of proteins that were ingested.

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