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February 1950

MONILIAL GRANULOMA: Report of a Case and Review of the Literature

Author Affiliations


From the Section of Dermatology, Department of Medicine, University of Chicago (Chief of Service, Dr. Stephen Rothman).

Arch Derm Syphilol. 1950;61(2):297-310. doi:10.1001/archderm.1950.01530090127012

MONILIAL granuloma is a rare specific disease entity resulting from Candida albicans infection. It begins in infancy or early childhood, often as simple oral thrush, and ultimately involves three sites: the oral mucosa, the finger nails and paronychial tissues and the skin of the scalp and face. The skin of the trunk and extremities is rarely involved. In contrast to the banal superficial forms of moniliasis, such as thrush, perlèche, erosio interdigitalis blastomycetica and other intertriginous eruptions, monilial granuloma is characterized by an inflammatory reaction extending into the corium and consisting of granulation tissue similar to that in the deep mycoses.

This report is based on observation of 1 case by us, and on reports of 13 cases uncovered in the literature.


G. S., a 7 year old white boy, was first seen in February 1948, with the history of "growths" on the skin since the age