It is well known that certain heavy metals are therapeutically efficacious for lichen planus. Mercury has long been used in the therapy of this disease. In fact, Sutton and Sutton1 "found mercury as originally recommended by Liveing superior to arsenic" and stated that "it is best given in the gluteal muscles." Wright2 found that gold given intravenously in the form of gold and sodium thiosulfate (25 to 50 mg. weekly) gave quick relief from itching and resulted in rapid involution of the eruption in the more acute and recent cases of lichen planus. Grossman, according to Sutton and Sutton,1 reported bismuth valuable. Sonck3 treated 29 patients with lichen planus with intramuscular injections of bismuth. Of these 38 per cent made a complete recovery, 41.4 per cent improved and 29.4 per cent did not improve. Conrad, Conrad, Mapother and Weiss4 treated 25 patients who had lichen
WRIGHT CS, GROSS ER. ORAL BISMUTH THERAPY FOR LICHEN PLANUS. Arch Derm Syphilol. 1950;61(3):489–491. doi:10.1001/archderm.1950.01530100133021
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