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Chronic Porphyria and Asymptomatic Neurosyphilis. Presented by Dr. Norman N. Epstein.
D. D., a 44 year old white man, first noted a red color of the urine two and a half years ago, concomitant with thickening and yellowish pigmentation of the right side of the neck. Bullous eruptions appeared on the backs of the hands, wrists and neck one and a half years ago. These lesions had recurrent intermittently since, without complete clearing at any time. Bullous lesions definitely were associated with trauma at times but less so in the last six months, when similar lesions appeared on the face. There has been a loss of over 30 pounds (14 Kg.) in the past year, as well as anorexia, vague abdominal pains, constipation and weakness. There are numerous vesicles and bullae on the backs of the hands, wrists, neck and face, with scarring. Yellow-brown pigmentation with poikilodermic changes is present
Keddie FM, Schmidt OEL, Rees RB. SAN FRANCISCO DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1950;61(3):517–519. doi:10.1001/archderm.1950.01530100161030
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