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Article
April 1950

COMPARATIVE ANALYSIS OF THE MUCOCUTANEOU-SOCULAR SYNDROMES: Report of Eleven Cases and Review of the Literature

Author Affiliations

BALTIMORE

From the Department of Dermatology and Syphilology, University of Maryland School of Medicine.

Arch Derm Syphilol. 1950;61(4):539-560. doi:10.1001/archderm.1950.01530110005001
Abstract

FREQUENT reference has been made in the literature relative to a syndrome of unknown etiology consisting of lesions occurring in the eyes and mouth and on the genitalia. This syndrome has been called by various authors Behcet's disease, Stevens-Johnson disease, Reiter's disease and ectodermosis erosiva pluriorificialis. A critical review of the features of these symptom groups as recorded by the various authors indicates the pronounced similarity which exists between all of them and suggests that according to the modern concept they are all probably variants of the same disease entity, erythema multiforme exudativum. It is our intention to attempt to clarify this contention by discussing each so-called entity individually, then by making a comparison of them all and finally by presenting a report on 11 cases.

BEHCET'S DISEASE

In 1937, Behcet1 gave his original description of a disease picture in which there were associated genital, oral and

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