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April 1950

SPINDLE CELL EPIDERMOID CARCINOMA: Report of Five Cases in Patients Who Had Never Been Exposed to Roentgen Rays

Author Affiliations


From the Division of Dermatology of the Yale University School of Medicine.

Arch Derm Syphilol. 1950;61(4):633-647. doi:10.1001/archderm.1950.01530110099007

WITH THE publication by Sims and Kirsch1 of a report of 2 cases a report of 2 cases of spindle cell epidermoid carcinoma, attention has again been called to this unusual and strange type of epithelioma. Sims and Kirsch also repeated the assertion of previous writers that this type of neoplasm occurs in epithelium damaged by chronic radiodermatitis and is probably the result of the previous exposure to roentgen rays. This is a report of 5 cases of such cancers occurring in patients who had never been exposed to roentgen rays or radium.

Spindle cell epidermoid carcinoma of the skin, of the type reported in this paper, was first reported in this country in 1935 by Martin and Stewart.2 They reported in detail 8 cases, in 6 of which the patient had received roentgen ray therapy (5 of these persons showing clinical evidence of chronic radiodermatitis) and in 1 of which the patient had been treated with radium and had

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