[Skip to Navigation]
Article
April 1950

PROPIONATE-CAPRYLATE MIXTURES IN TREATMENT OF DERMATOPHYTOSIS

Author Affiliations

LITTLE ROCK, ARK.

Arch Derm Syphilol. 1950;61(4):669-673. doi:10.1001/archderm.1950.01530110135013
Abstract

Interest in dermatophytosis was intensified during the second world war by the discovery that this condition ranked second among the cutaneous diseases which accounted for no less than 8 per cent of all hospital admissions in the Army and Navy. The Council on Pharmacy and Chemistry of the American Medical Association appointed a committee (Drs. Weidman, Emmons, Hopkins and Lewis)1 which submitted a report on "The War and Dermatophytosis" in The Journal of the American Medical Association for July 14, 1945. One of the noteworthy comments in this report is the naming of sodium propionate as a useful fungicide.

Fatty acid therapy for mycotic infections was introduced by Peck and his associates.2 This step followed the demonstration by Peck and Rosenfeld3 that members of the fatty acid series from Ci to C11 were fungistatic and often fungicidal in proper concentration. As normal constituents

Add or change institution
×