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May 1950


Author Affiliations

President; Secretary Nov. 18, 1948

Arch Derm Syphilol. 1950;61(5):868-875. doi:10.1001/archderm.1950.01530120159024

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Parkes Weber's Syndrome. Presented by Dr. William M. Siskind.

M. S., a single woman aged 22, states that the left lower limb has been enlarged since birth. Otherwise she has always been in good health. The mother died of amyotrophic lateral sclerosis and the father of a renal ailment at the age of 65. The patient has 3 older brothers and 2 older sisters, all living and well. No member of the family has a similar skin disease.

The enlargement of the left lower extremity was noticed immediately after birth. At the age of 12 there developed varicose veins of the left leg. Four years later the patient had a ligation of the saphenous vein. The operation was not successful, and the veins of the leg became more prominent.

The left lower extremity is thicker and heavier than the right. The left foot appears larger than the right. There is

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