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Article
June 1950

TREATMENT OF LUPUS ERYTHEMATOSUS WITH CALCIFEROL, ANTIBIOTICS AND GOLD PREPARATIONS

Author Affiliations

BROOKLYN

From the Department of Dermatology and Syphilology of the New York University Post-Graduate Medical School, Dr. Marion B. Sulzberger, chairman, and the Skin and Cancer Unit of University Hospital.

Arch Derm Syphilol. 1950;61(6):909-912. doi:10.1001/archderm.1950.01530130027007
Abstract

EXPERIENCE with calciferol (vitamin D2) in the treatment of lupus erythematosus has been limited to a few therapeutic trials. Charpy,1 who with Dowling2 was one of the first proponents of calciferol therapy, found this agent ineffective in lupus erythematosus. Popoff and Ivanov3 likewise found calciferol of no benefit in 3 cases of lupus erythematosus of the mucous membranes.

There have been surprisingly few publications dealing with penicillin therapy of the disease, although the consensus is that penicillin is of little or no value in the management of either the acute or the chronic form of lupus erythematosus. Franks4 administered penicillin parenterally in 2 cases of chronic discoid lupus erythematosus. In 1 the eruption remained unchanged, and in the other the disease "became much worse, as shown by the increase in sedimentation rate and the dissemination of the lesions." Kolmer5 and Strakosch6 each obtained

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