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June 1950


Author Affiliations

President; Secretary Feb. 9, 1949

Arch Derm Syphilol. 1950;61(6):1066-1070. doi:10.1001/archderm.1950.01530130184022

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Hereditary Hemorrhagic Telangiectasia. Presented by Dr. Chester N. Frazier, Boston.

J. S., a 54 year old white man of Syrian birth, gave a history of repeated attacks of epistaxis of varying grades of severity for twenty-six years. Two years after the onset of epistaxis, vascular lesions first appeared on the face. These slowly increased in number and in size. The patient's mother had similar lesions and repeated nasal hemorrhages. No other member of the family was known to be affected. Between 1925 and 1949 the patient had been treated many times for epistaxis. Hemorrhage was so profuse on several occasions as to require repeated blood transfusions. Bleeding was observed only from the nasal cavity.

Examination reveals many telangiectases and multiple hemangiomas on the patient's face, with the malar regions most profusely affected. The angiomas are as large as 6 to 8 mm. in diameter and elevated from 1 to 3

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