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July 1950

RETICULUM CELL SARCOMA: Report of a Case, with Comment on Its Genesis

Author Affiliations


From the Department of Dermatology and Syphilology, New York University-Bellevue Medical Center, and the Dermatological Service of the Third (New York University) Medical Division, Bellevue Hospital, service of Dr. Frank C. Combes.

Arch Derm Syphilol. 1950;62(1):69-84. doi:10.1001/archderm.1950.01530140073008

THIS IS the report of a case of reticulum cell sarcoma involving the skin and testes, with fatal outcome after a duration of one year. Lymph nodes were not primarily affected, although later the inguinal nodes were involved secondarily by extension from the testicular lesions. Permission for autopsy was not obtained, but physical and roentgenologic examinations revealed no other lymph node enlargement. Clinically the lesions resembled those of mycosis fungoides d'emblee or Spiegler-Fendt sarcoid. Histologically, the earlier biopsies showed a picture consistent with that described for Spiegler-Fendt sarcoid, while later ones of specimens from testes and skin revealed changes typical of reticulum cell sarcoma.

This observation raises the question of the correlation between the clinical and the histologic picture of the lymphoblastomas involving the skin primarily. In 1902, Breakey,1 referring to the cutaneous manifestations of the lymphoid diseases, stated that "while the study of these dermatoses has been prosecuted

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