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Article
August 1950

STREPTOMYCIN TREATMENT OF GRANULOMA INGUINALE

Author Affiliations

NORFOLK, VA.

Arch Derm Syphilol. 1950;62(2):261-264. doi:10.1001/archderm.1950.01530150083009
Abstract

During period from November 1947 to June 1949, we had the opportunity to follow 76 patients having granuloma inguinale treated with streptomycin.1 Over 60 per cent of these persons were observed for periods longer than six months after the initial course of streptomycin was administered. Therefore, this report offers significant information concerning the results of treatment.

It is not the purpose of this paper to review the literature on this subject, since this has been adequately done by several authors.2 Moreover, it is beyond the scope of this presentation to describe the various clinical manifestations of the disease, since this aspect also has been adequately covered.3

The following criteria were used for inclusion of cases in this study: 1. Clinical diagnosis was accepted only if intracellular Donovan bodies were identified from material obtained from scraping. 2. All other venereal diseases were treated adequately before therapy for

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