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Article
September 1950

TREATMENT OF DERMATITIS HERPETIFORMIS RESISTANT TO USUAL THERAPY

Author Affiliations

WOOD, WIS

From the Department of Dermatology, Veterans Administration Center, Wood, Wis., and the Marquette University School of Medicine, Milwaukee.

Arch Derm Syphilol. 1950;62(3):422-424. doi:10.1001/archderm.1950.01530160076012
Abstract

THE CASE to be presented is of interest because of the following points: After failure of numerous forms of therapy a good response to sulfapyridine was followed by the development of intolerance and fastness to this medication. Treatment with potassium arsenite (Fowler's) solution was completely ineffective, resulting in unusually rapid development of palmar keratoses. The administration of aureomycin, penicillin and chloramphenicol (chloromycetin®) was completely ineffective. Terfonyl® (a combination of sulfadiazine, sulfamerazine and sulfamethazine in equal amounts) therapy was followed by immediate clearance of the lesions.

REPORT OF A CASE

S. G., a 34 year old shipping clerk, was admitted to the hospital in October 1949 because of recurrent dermatitis. The disease had been intermittently present for a period of four years, a diagnosis of dermatitis herpetiformis having been made in 1947, at which time a biopsy of the skin revealed changes compatible with this

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