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September 1950


Author Affiliations

Civilian Consultant in Dermatology and Syphilology, United States Naval Hospital OAKLAND, CALIF.; (MC), U.S.N.R.; (MC), U.S.N.R.

From the Dermatology Service, United States Naval Hospital, Oakland, Calif.

Arch Derm Syphilol. 1950;62(3):443-448. doi:10.1001/archderm.1950.01530160097019

We report this case of the Ehlers-Danlos syndrome because of the general interest such a case presents to the practitioner of medicine. This disease process is not a rarity, and yet few cases have been reported in which all components of the syndrome were present.

Early descriptions of the syndrome were made by Ehlers, by Cohn and by Danlos.1 Since that time, many more cases have been reported, a larger proportion now coming from the American literature. In 1936 Ronchese2 reviewed the literature, finding 27 previous cases and adding 3 of his own. Through this review it was learned that not all cases previously reported satisfied the criteria originally prescribed by Ehlers and Danlos, namely (1) dermatorrhexis (fragilitas cutis), (2) dermatochalasis (laxitas cutis) and (3) arthrochalasis (laxitas articularis). Speculation still exists concerning the etiology of this disease. The histopathologic picture varies according to the authors who