ALTHOUGH seldom given the publicity of the other venereal diseases, granuloma inguinale probably offers a greater sociologic1 and treatment problem in the average case than any of the other venereal diseases. Until recent years, there has been no therapeutic agent available which would give satisfactory, sustained and reasonably rapid improvement in these cases.
In 1947 Greenblatt and his co-workers2 at the University of Georgia reported outstanding results in the treatment of granuloma inguinale with streptomycin. Since that time, numerous authors3 have reported equally good results with this drug. It was only natural that investigators would further pursue the study of the response of granuloma inguinale to the more recent antibiotics which were being presented to the medical profession. Reports are now beginning to appear in the literature giving the results of the treatment of granuloma inguinale with aureomycin4 and chloramphenicol (chloromycetin®),5
ZISES M, SMITH GC. GRANULOMA INGUINALE AND ITS TREATMENT WITH ORAL AUREOMYCIN. AMA Arch Derm Syphilol. 1950;62(5):642–647. doi:10.1001/archderm.1950.01530180031006
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