Granuloma fissuratum was distinguished as a clinical entity by Sutton Jr.1 in 1932, and since then a small number of cases have been reported. Sutton described the lesion as a circumscribed, firm, whitish, fissured, granulomatous new growth occurring in the labioalveolar fold. The lesion is discoid, smooth, rounded and slightly raised, being approximately a centimeter in diameter, lacking an inflammatory areola and folded similarly to a bent coin, so that the fissure in the bend is continuous at both sides with the labioalveolar sulcus. Symptoms are slight. Sutton's two original cases involved the superior labioalveolar sulcus, but other cases have been described subsequently involving the inferior sulcus. The etiology is unknown, but several authors have incriminated dentures as an etiologic contributing factor, even though the dentures did not touch the lesion; streptococcic origin is also postulated. Sutton classified these lesions in the granuloma pyogenicum group. For
MOPPER C, ROGIN JR. GRANULOMA FISSURATUM HEALED BY PENICILLIN TROCHES. AMA Arch Derm Syphilol. 1950;62(5):715–716. doi:https://doi.org/10.1001/archderm.1950.01530180104029
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