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December 1950

PEMPHIGUS VULGARIS: A Clinicopathological Study of One Hundred Cases

Author Affiliations

In Collaboration with Jerome J. Kaufman, M.D., and Socorro A. Simuangco, M.D. NEW YORK

From the Department of Dermatology and Syphilology of the New York University Post-Graduate Medical School, Dr. Marion B. Sulzberger, chairman, and the Service of Dermatology and Syphilology of Bellevue Hospital, Dr. Frank C. Combes, chief of service.

AMA Arch Derm Syphilol. 1950;62(6):786-802. doi:10.1001/archderm.1950.01530190020002

IN 1941 Gellis and Glass1 reported on a survey of 170 patients with pemphigus admitted to Bellevue Hospital from 1911 to 1941. In part they came to the following conclusions:

  1. The national origins of patients were Russia, 27.2 per cent; United States, 24.8 per cent; Italy, 8.2 per cent, and Austria, 8.2 per cent.

  2. The racial stock of patients was Jewish, 49 per cent; Italian, 11 per cent; Negro, 7 per cent, and English-speaking races, 6 per cent.

  3. The trunk was the most frequent site of the initial lesion, with the mouth a close second.

  4. Analysis of necropsies performed on nine patients showed pathological changes in the adrenal glands in three. The liver in all showed fatty degeneration.

  5. No specific treatment routine other than efficient nursing seemed to influence favorably the general course of the disease.

In addition, in 1942 Lever and Talbott

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