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Lymphogranuloma Venereum with Negative Reaction to Frei Test. Presented by Dr. Orlando Canizares.
L. M., a Negro woman aged 27, was admitted to Bellevue Hospital on May 16, 1949, with elephantiasis and fibrosis of the vulva and open ulcerative granulomatous lesions of the natal cleft. She complained of pain on defecation. Review of admissions to Kings County Hospital indicated that she had been treated for lymphogranuloma venereum in 1942, 1943 and 1944 and that in 1945 a colostomy had been performed for rectal stricture. She was readmitted in 1948 with the same complaint and received sulfadiazine and estrogens.In 1942 the reaction to the Frei test was reported as positive. A biopsy was also performed at this time and reported as "compatible with lymphogranuloma venereum." Clinical and laboratory studies at Bellevue Hospital revealed the following results: Frei and Ducrey reactions were consistently negative. The complement fixation test for
Costello MJ, Sachs W. NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILIS. AMA Arch Derm Syphilol. 1951;63(1):138–142. doi:10.1001/archderm.1951.01570010141016
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