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January 1951


AMA Arch Derm Syphilol. 1951;63(1):146-166. doi:10.1001/archderm.1951.01570010149018

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Leiomyoma Cutis. Presented by Dr. F. E. Senear and Staff.  R. O., a 37 year old white woman, was seen with three small nodules on the right forearm of 21 years' duration. The lesions had been increasing in size gradually and in the previous six months had developed a "pinching feeling." Pain was experienced on exposure to cold. There had been no previous treatment.The three grouped pea-sized nodules on the extensor surface of the right forearm were firm and brownish red. They were moderately tender to touch.Examination of a section taken from one nodule on the right forearm revealed interlacing bundles of smooth muscle traversing the corium in various directions. The muscle fibers contained centrally located, thin, very long, blunt-edged nuclei. The muscle bundles were easily distinguishable from the collagenous tissue. A Van Gieson—stained section, also submitted for study, revealed the muscle fibers as yellow bundles in contrast

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