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A Case for Diagnosis: Mesodermal Nevus? Presented by Dr. Nelson Paul Anderson.
A. R., a white woman aged 38, has had a group of symptomless lesions in the left lumbar region for the last eight years, consisting of 20 to 30 elevated large papular and nodular, relatively soft yellowish lesions. Biopsy was made of one of these lesions.
Dr. Kenneth Stout: The lesions, I believe, are nevoid and probably examples of epidermal nevi. Microscopically the epidermis showed the structure of seborrheic keratosis.Dr. L. H. Winer: I thought that histologically the condition resembled epidermal nevus. Sometimes one might attempt to differentiate this disorder from seborrheic keratosis by the presence in such a nevus of more keratin in proportion to the epithelial proliferation, there being in seborrheic keratosis more epithelium and less keratin. Of further interest were the changes in the papillary bodies of the cutis. These bodies were so