Three cases of irritation and local sensitization to bacitracin ointment are reported.
REPORT OF A CASE
A white man 47 years old, who had had recurring attacks of infectious eczematoid dermatitis on the side of his face and ear, was given bacitracin ointment. Within a few hours the patient called to complain of severe burning and itching from the ointment. Medication was stopped. Six months previously aureomycin ointment had been used with similar irritating results.Four weeks after the attack of dermatitis, 48-hour patch tests with bacitracin and with a petrolatum base gave negative reactions.
A white woman aged 50, who had impetigo contagiosa on the left side of her face and neck, was given bacitracin. Pronounced weeping was seen on the area covered by the bacitracin 24 hours after it was first used. When the dermatitis healed, 48-hour patch tests with bacitracin and a petrolatum base gave
REICHES AJ. TOPICAL BACITRACIN SENSITIVITY: Report of Three Cases. AMA Arch Derm Syphilol. 1951;63(4):505–506. doi:10.1001/archderm.1951.01570040099022
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