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April 1951

ACRODERMATITIS PUSTULOSA PERSTANS: Persistence for Twenty-One Years, Since the Age of Three Years

Author Affiliations


AMA Arch Derm Syphilol. 1951;63(4):506. doi:10.1001/archderm.1951.01570040100023

Sachs and Field1 recently focused our attention on the fact that acrodermatitis pustulosa perstans may exist in childhood. They reported its occurrence in a 12 year old child, in whom it had been present since the age of 2. This report is of a case having its onset at the age of 3 (corroborated by parents) and persisting without clearing completely for 21 years.

REPORT OF A CASE  R. M. is a white multipara aged 24 who has had a typical picture of acrodermatitis pustulosa perstans of the palms since she was 3 years of age. Her palms showed diffuse large erythematosquamous patches studded with tiny deep vesiculopustules. Biopsy showed the characteristic large pustule in a slightly acanthotic prickle cell layer, filled with polymorphonuclear leukocytes and debris. There was a mild infiltration of small round cells with a few polymorphonuclear leukocytes in the upper part of the cutis, limited

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