HUMAN blood plasma contains a complex mixture of proteins.1 Only since the introduction of electrophoretic analysis by Tiselius,2 has a thorough and reliable study of the plasma proteins been possible. Before then the only practical method had been the determination of albumin and globulin by the salting-out method of Howe,3 which, in comparison with electrophoretic analysis, is crude and often misleading. Several reviews of the data obtained in various diseases by electrophoretic analysis of the blood plasma have been published in recent years,4 but the number of determinations in dermatologic conditions is still small.
In this communication the electrophoretic data obtained by us in various dermatologic conditions will be presented and compared with the results reported by other authors. In many instances the data obtained with the Howe method by previous authors and by ourselves will also be given, in order to afford an opportunity for