Actinomycosis. Presented by Dr. A. Benson Cannon.†
J. M., a woman aged 21, was previously presented at the January meeting. All lesions are now healed, with the exception of a granulating area on the right cheek 1 cm. in diameter. Treatment, which continues, has consisted in the following: (1) penicillin—46 daily injections to date, beginning with 600,000 units and gradually increasing (The last 27 injections have consisted of 1,800,000 each, for a total so far of 65,700,000 units [January 12 to the present]); (2) sulfadiazine —4 Gm. daily for six days (January 15 to 21), discontinued because of nausea; (3) aureomycin —2 capsules four times daily for four days (January 22 to 26), discontinued because of nausea and gas; (4) chloramphenicol (chloromycetin®)—2 capsules four times daily for 15 days (January 26 to February 9), discontinued because of low grade fever; (5) sodium iodide—1 Gm. intravenously daily for 12 days