Acrodermatitis pustulosa perstans has, since its recognition, been a most interesting and baffling skin disorder to treat. The above name, given by Sachs, MacKee and Rothstein,1 emphasizes the persistency of the disease in spite of all usual therapeutic measures. So also does the synonym recalcitrant pustular eruptions of the palms and soles.2 The diversity in thought as to etiology is emphasized by the other synonyms, namely, pustular psoriasis of Barber3 and pustular bacterids of Andrews and Machacek.4 The etiology is still unknown. The histopathological picture is now clear, thanks to Wilbert Sachs.5
Recently such unusual success was obtained in clinically clearing consecutive cases of acrodermatitis pustulosa perstans that it was thought worth while to record the method of treatment so that more widespread evaluation might be undertaken.
These cases showed the typical clinical appearance of tiny, deep vesiculopustules studding erythematous, slightly scaly patches on the