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Article
October 1951

GENERALIZED MILIARIA RUBRA ASSOCIATED WITH ABNORMAL VITAMIN A METABOLISM

AMA Arch Derm Syphilol. 1951;64(4):411-416. doi:10.1001/archderm.1951.01570100028003
Abstract

IN RECENT years it has been shown clinically and experimentally1 that miliaria rubra is a phenomenon of sweat retention resulting from hyperkeratotic plugging of the orifices of the sweat glands. The patient whose case we are reporting had generalized miliaria rubra associated with anhidrosis and subnormal absorption and utilization of vitamin A.

REPORT OF A CASE  The patient was a white male physician, 64 yr. old, from Illinois, whose chief complaint was that of generalized pruritus of two-and-a-half years' duration and intolerance to heat of one-year's duration. The generalized pruritus either was more intense during hot weather or was associated with physical exertion. Roughness of the skin was noted by the patient during this time, but no eruption was observed until a year before study at the Mayo Clinic, when an urticarial, macular, and erythematous dermatosis developed first on the exposed portions of the body and gradually progressed to

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