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Article
October 1951

IDIOPATHIC HYPERLIPEMIA WITH SECONDARY XANTHOMATOSIS: Report of a Case

Author Affiliations

BROOKLYN

From the Departments of Dermatology and Medicine, State University of New York, State University Medical Center at New York, College of Medicine.

AMA Arch Derm Syphilol. 1951;64(4):434-436. doi:10.1001/archderm.1951.01570100051008
Abstract

IN A RECENT publication1 Thannhauser stated, "The clinical syndrome of idiopathic hyperlipemia in adults with secondary eruptive xanthoma, occasionally accompanied by glycosuria, hitherto was not established as a clinical entity but often confused with hyperlipemia in severe untreated diabetes and accordingly classified as `xanthoma diabeticorum' or `diabetic hyperlipemia.' "

The term hyperlipemia as used here indicates an opaque, milky blood serum in which the neutral fat content is markedly increased; cholesterol and other lipids are generally elevated to a lesser degree. Hyperlipemia may be idiopathic or associated with, and probably due to, other diseases. In both instances xanthoma may appear or "erupt" when there is a high degree of lipemia and regress when it subsides.

Since the occurrence of xanthoma in idiopathic hyperlipemia is a manifestation of the underlying hyperlipemia, its appearance clinically and histologically is the same as that of xanthoma diabeticorum. The lesions are discrete papules, generally pinhead

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