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Article
October 1951

EVALUATION OF A NEW DRUG FOR TOPICAL THERAPY OF TINEA CAPITIS

AMA Arch Derm Syphilol. 1951;64(4):444-448. doi:10.1001/archderm.1951.01570100061011
Abstract

THE INCREASE in the incidence of tinea capitis of the anthropophilic type, which has often assumed epidemic proportions during the past several years, has clearly demonstrated the need for a simplified form of effective treatment.

Many therapeutic approaches have been abandoned as unsatisfactory, and others have met with varying degrees of success. For example, the use of trichophytin injections produced equivocal results and was discarded.1 Similarly, the topical administration of hormones proved of only dubious value.2 The proper application of trimethyl cetyl ammonium pentachlorphenate (T. C. A. P.)3 required diligent care for several hours daily, and the use of this product was therefore relinquished as impracticable. While fatty-acid compounds have merits in the treatment of mycoses of the glabrous skin, they are ineffectual against tinea capitis. Salicylanilide ointment is attended by better results, but it still leaves much to be desired. Against this background, we welcomed the

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