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October 1951


AMA Arch Derm Syphilol. 1951;64(4):523-524. doi:10.1001/archderm.1951.01570100140023

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Onycholysis with Pigmentation. Presented by Dr. Charles J. Courville.  A white woman, aged 25, is presented, with orange and brownish discoloration and varying degrees of separation of the nail plates of all fingernails of both hands, which began six weeks ago and extended to all fingernails. She has been using various unnamed types of nail polish and nail-polish base. There is no history of trauma or other disease except asthma. The toe nails are not affected. No other skin lesions are seen.

DISCUSSION  Dr. Herman Pinkus: Base coats can impart permanent luminescence to fingernails under filtered ultraviolet light rays. The color effect resembles that caused by ingestion of quinacrine (atabrin®) hydrochloride. The base coats themselves are not luminescent and do not change the appearance of the nails when freshly applied. Either these plastics cause some change of the nail substance, or they permit a fluorescent dye which may be in

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