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November 1951


AMA Arch Derm Syphilol. 1951;64(5):573-579. doi:10.1001/archderm.1951.01570110043006

OUR EXPERIENCE confirms that of others,1 showing that oral administration of cortisone acetate is as effective as its administration by intramuscular injection. This circumstance is of great importance to every physician and private practitioner; and it is especially important to the dermatologist, who treats a large proportion of his patients in an ambulatory state.

It therefore appears indicated at this time to present a brief review and evaluation of our experiences with the therapeutic effectiveness of orally administered cortisone acetate in various dermatoses. A total of 32 patients from the private practice of one of us (M. B. S.) are reported upon in the accompanying table. These represent all the patients treated by this modality since October, 1950, when we began administering cortisone acetate by the oral route.

At first, the hormone was prepared for oral administration by mixing the cortisone acetate solution2 with equal parts of isotonic