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Article
November 1951

CONGENITAL ICHTHYOSIFORM ERYTHRODERMA: A Report of Two Cases in Siblings, One Complicated by Kaposi's Varicelliform Eruption

AMA Arch Derm Syphilol. 1951;64(5):611-619. doi:10.1001/archderm.1951.01570110081012
Abstract

TWO CHILDREN in the same family with congenital ichthyosiform erythroderma have recently been available for detailed study. This condition is not seen often, and little information on the subject has been published in the current medical literature. In addition, one patient had what is thought to be the first recorded occurrence of Kaposi's varicelliform eruption as a complication of this disease, and his case is one of the few on record with complete autopsy findings.

Congenital ichthyosiform erythroderma was described by Brocq1 in 1902, although it had been recognized as a clinical entity by Vidal2 in 1882. However, according to Bruhns,3 the first case was reported by Sangster in 1895. Important reviews of the literature were made by MacKee and Rosen4 in 1917 and by Weiss and Tobias5 in 1925. Laymon and Murphy6 in 1948 presented a detailed report of the clinical features, histological

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