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December 1951

LYMPHOCYTOMA OF THE SKIN: Report of an Unusual Case (Lymphocytoma Tumidum)

Author Affiliations


AMA Arch Derm Syphilol. 1951;64(6):761-766. doi:10.1001/archderm.1951.01570120096010

IN TWO recent papers the entity of lymphocytoma of the skin was discussed for the first time in the American dermatologic literature.1 The disease has been recognized for many years, however, both as lymphocytoma and as Spiegler-Fendt sarcoid, as reported by Lewis2 and others. In 1943 the subject was comprehensively reviewed in a monograph by Bäfverstedt.3 This author, like Lewis, distinguished two clinical types: the isolated or regionally localized type, and the multiple disseminated type. Clinically, lymphocytoma presents a variable picture, with lesions usually on the face, characterized by small size, slow growth, absence or paucity of subjective symptoms, and no intrusion of cancerous change. Histologically, the lesions consist of a highly differentiated lymphoid tissue, with or without germinal centers. Pursuing a benign course, they may persist indefinitely or they may disappear spontaneously. As a rule they exhibit marked sensitivity to roentgen irradiation.

The following case is

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