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Pseudoxanthoma Elasticum. Presented by Dr. M. H. Samitz and (by invitation) Dr. J. Coletti, and Dr. M. Greenberg.
N. W., a Negro woman aged 57, well developed, fairly well nourished, and in no distress, presents periumbilical lesions, none in the umbilicus proper. They are firm, tender, and plaque-like and radiate laterally from the umbilicus. There is abnormal elasticity. The axillae and sides of the neck show increase in elasticity, but no papules or plaques are found in these areas. The patient first noticed pruritic, at times painful, papules around her umbilicus in 1947. During the past six months they have enlarged and become plaque-like and more tender to palpation.The patient has mild diabetes mellitus, but she is not taking insulin. She has pelvic inflammatory disease and erosion of the cervix.Serologic tests for syphilis elicited negative reactions. Results of urinalysis were normal, and the blood count was