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March 1952


Author Affiliations


AMA Arch Derm Syphilol. 1952;65(3):303-315. doi:10.1001/archderm.1952.01530220044004

HIDRADENITIS suppurativa and the more severe types of acne, such as acne conglobata and dissecting cellulitis of the neck and scalp, not infrequently occur in the same persons. These disorders have been described as distinct entities; however, in clinical characteristics and in the course of the disease, they have many similarities which indicate a close relationship among them. They may be considered as regional counterparts in which the acne process is manifested in its extreme variants and in its more fulminating forms. Acne conglobata, dissecting cellulitis, hidradenitis, and other variants of acne have these features in common: functional glandular hyperplasia of the apocrine gland and pilosebaceous apparatus; double comedo formation and impaction of the follicular orifice; bacterial invasion with suppuration and undermining of the loose areolar tissue, and eventual healing with cicatrization and not infrequent keloid formation.

This presentation is concerned with a correlation of various aspects of the