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To the Editor:—I have received numerous inquiries about my discussion in the Archives (63:786 [June] 1951) of the treatment of vitiligo.
In 1947, I. R. Fahmy and Hamed Abu Shady isolated from the fruits of Amni majus two crystalline compounds, to which the names amoidin (C12H8O4) and ammidin (C16H14O4) were given. These are really bitter substances and not alkaloids, as they do not contain a nitrogen group.
The available literature to date is as follows:
Fahmy, I. R., and Abu Shady, H.: The Isolation and Properties of Ammoidin, Ammidin, and Majudin and Their Effect in the Treatment of Leucoderma, J. Pharm. & Pharmacol. 21:449-503, 1948.
El Mofti, A. M.: A Preliminary Clinical Report on the Treatment of Leucoderma with Amni Majus Linn, J. Roy. Egyptian M. A. 31:651-665 (Aug.) 1948.
El Mofti, A. M.: Further