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Generalized Amyloidosis. Presented by the Department of Dermatology, University of Michigan.
Localized Cutaneous Amyloidosis. Presented by Dr. A. E. Schiller, Detroit, and Dr. H. H. Holman, Detroit.
L. B., a white man aged 56, had various medical and surgical treatment for duodenal and gastric ulcers since 1915. In none of the resected material was amyloid tissue ever found.
Physical examination shows excoriated reddish-brown papules, with underlying lichenification and brawny pigmentation.
There were no abnormalities revealed by general laboratory examination. A sulfobromophthalein sodium test revealed 35% of the dye retained at a 5-minute interval and less than 5% retained after 30 minutes. Reaction to Congo red injection was positive. The diagnosis from the biopsy was reported as amyloidosis cutis, lichenoid.
DISCUSSION OF TWO PRECEDING CASES
Dr. Herman Pinkus, Detroit: I wish to suggest a technical feature in amyloidosis. Leave the paraffin sections, just as they are, in the methylrosaniline chloride
Schiller AE, Holmes RH. CENTRAL STATES DERMATOLOGICAL SOCIETY. AMA Arch Derm Syphilol. 1952;65(3):364–366. doi:10.1001/archderm.1952.01530220105016
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