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March 1952


Author Affiliations

President; Secretary; Recorder Feb. 14, 1951

AMA Arch Derm Syphilol. 1952;65(3):371-372. doi:10.1001/archderm.1952.01530220112018

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Presentation of all cases at this meeting was made by Dr. F. Blumenthal and staff, Department of Dermatology, Wayne County General Hospital, Eloise.


R. M., a 50-year-old Negro man, a janitor, complained of sores on the neck, the shoulders, and the left eyebrow, which had been gradually increasing since November, 1949. He recalled a sore on the back of the neck seven years ago which required 2 to 3 years for healing. He appears chronically ill, but no abnormalities are apparent except the skin lesions which are large ulcerative granulomatoses with raised borders.

Laboratory findings indicated a microcytic hypochromic anemia. Biopsy findings were compatible with blastomycosis. Roentgenograms of the chest revealed a peribronchial infiltration not typical of blastomycosis. This resolved later.

The use of iodides resulted in healing of the sores, but toxicity developed. Local administration of 1% "propamidine" (a proprietary compound, 4,4′diamidinodiphenoxy-propane dihydrochloride) did not accelerate

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