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Article
April 1952

WEBER-CHRISTIAN DISEASE OCCURRING IN A NEGRO WOMAN

AMA Arch Derm Syphilol. 1952;65(4):487-489. doi:10.1001/archderm.1952.01530230111016
Abstract

The purpose of this paper is to report another case of Weber-Christian disease and to present what we believe to be the second case reported in a Negro.1 In addition, the unusual feature previously reported2 of progressive necrosis of the pannicula adiposa leading to spontaneous rupture and drainage of the subcutaneous nodules was also observed.

Weber-Christian disease is of unknown origin, and it is not the purpose of this report to discuss the controversial theories as to its cause.3 However, the sudden and often explosive character of the appearance of these nodules makes one postulate an allergic mechanism.

Pfeiffer first described this condition in 1892, and Weber3e later reported a case in which he labeled the condition relapsing nonsuppurative nodular panniculitis. In 1928 Christian,4 in his report of the third case, suggested adding "febrile" to Weber's definition. Since then it has been referred to as

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