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April 1952


AMA Arch Derm Syphilol. 1952;65(4):490. doi:10.1001/archderm.1952.01530230114017

It is the purpose of this report to describe the successful use of podophyllin in treatment of 13 patients with verruca plantaris, of whom 11 were cured. The patients remained ambulatory during the treatment, and no discomfort was encountered. There has been no recurrence after four to six months' observation of the 11 cured patients.

In 1948, Kurtin and Yantef 1 first reported the successful use of podophyllin in the treatment of plantar warts. Their method consisted of paring down the wart until bleeding points were encountered. The surrounding area was coated with collodion, and a drop of a 25% solution of podophyllin in liquid petrolatum was then placed into the concavity. A 2-in. (5-cm.) strip of well-flamed tape was placed over the lesion to macerate the area. This treatment was repeated at eight-day intervals, usually for three to four treatments. These authors reported 60% cures in a small series