Anaplastic Epithelioma. Presented by Dr. Frank C. Combes.
T. W., a woman aged 68, first noticed some itching in the vulval region two years ago. The exact location cannot at this time be determined but a cutaneous eruption appeared which gradually extended to involve most of the anogenital region. The pruritus later gave way in part to pain and soreness. Several x-ray treatments were given but seemed to increase the pain. The patient had a complete mastectomy on the left for cancer one year ago. The patient was first seen by me on March 21, 1951, with a mammillated, bright beefy red, granulomatous, precisely defined lesion which extended from the pubis posteriorly to the anus and laterally into either crural fold. The surrounding skin is of normal appearance. The entire lesion is moist and glistening. At many sites the tips of the mammillated papillae are pearl-white. There is no