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June 1952


AMA Arch Derm Syphilol. 1952;65(6):752-755. doi:10.1001/archderm.1952.01530250116015

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Localized Atopic Eczema (Commissures). Presented by Dr. George M. Lewis.

F. K., a woman aged 36, noticed a small fissure in the left corner of the mouth five years ago. Two or three years ago the right corner fissured. Both fissures have been persistent, pruritic, and tender at times and limit the opening of the mouth. There has been some improvement in the summer, but recently the condition has become worse. She has been given two x-ray treatments, two radium treatments, and several courses of therapy with vitamins B and C, without effect.

Redness and superficial fissuring extend 3 mm. from both corners of the mouth. There is a thin, irregular, white film over the left buccal mucous membrane. The right mucous membrane shows some whiteness in lines adjacent to the biting edge.

A mycologic examination gave negative results.

Treatment was started with administration of antihistaminic drugs by mouth

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