IN THE introductory article to the 1948 "Year Book of Dermatology and Syphilology," Sulzberger and Baer1 stated that
In modern studies it has been emphasized that anatomic and histopathologic morphologically discernible changes in the regions of sweat glands and pores merit equal or even closer attention than do functional changes or abnormalities of sweating.
Some of the earliest exploratory work related to the subject, which ranges from sudamina and miliaria rubra to thermogenic anhidrosis and tropical asthenia, was that of Robinson2 in 1884. He found in sections of sudaminal skin that the vesicles were formed in the horny layer and that they were in direct communication with sweat ducts. The rete around the vesicles and the glands and ducts themselves were normal. The disease was, in his opinion, due to increase in the production of sweat, together with some obstruction to its escape caused ordinarily by